Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?

Diagnosing gastrointestinal illnesses using fecal headspace volatile organic compounds.

Volatile organic compounds (VOCs) emitted from stool are the components of the smell of stool representing the end products of microbial activity and metabolism that can be used to diagnose disease. Despite the abundance of hydrogen, carbon dioxide, and methane that have already been identified in human flatus, the small portion of trace gases making up the VOCs emitted from stool include organ...

Letter: faecal volatile organic metabolites, promising biomarkers in inflammatory bowel disease and Letter: faecal volatile organic metabolites as novel diagnostic biomarkers in inflammatory bowel disease. Authors' reply.

Fecal Microbiota Transplantation in Inflammatory Bowel Disease.

The etiology of inflammatory bowel disease (IBD) is unknown, but it is thought to arise from an aberrant immune response to a change in colonic environment in a genetically susceptible individual. The intestinal microbiota are located at the complex interface of the epithelial barrier and are sensitive to changes in environmental factors, such as diets, drugs or smoking and signals derived from...

Could fecal calprotectin enter mainstream use for diagnosing and monitoring inflammatory bowel disease?

authors found that the overall accuracy for differentiating IBD from IBS or other types of colitis was 94% and 91% respectively for Quantum Blue ® (cutoff, 50 μg/g); 92% and 89% for EliA TM (cutoff, 50 μg/g); and 82% and 76% for RIDAS-CREEN ® (cutoff, 50 μg/g). The Quantum Blue ® Calprotectin and EliA TM Calprotectin results were significantly correlated with the CDAI (Spearman's rank correlati...

Neonatal Presentation of Unremitting Inflammatory Bowel Disease

Very-early-onset inflammatory bowel disease (VEO-IBD) has a distinct phenotype and should be considered a specific entity. VEO-IBD presents with very severe clinical pictures and is frequently known by an indeterminate colitis whose clinical remission is unmanageable. This study examines the case of a neonate with VEO-IBD, not responding to medical and surgical treatment. A 7-day-old Iranian fe...